A report has shown that genetic deletion, or mutation, of TET2 and TET3 in mouse B cells damps down the generation of functional IgG antibodies, decreasing the effectiveness of immune responses.
From https://www.sciencedaily.com/releases/2019/04/190426142049.htm
from
https://healthnews010.wordpress.com/2019/04/28/tet-proteins-regulate-factors-essential-for-normal-antibody-production/
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