A Potential Approach to Tackling CEL and CML Advanced Glycation End Products

Advanced glycation end-products (AGEs) form in tissues as a side-effect of the normal operation of cellular metabolism where it touches on the processing of sugars. There are many types of AGEs, most short-lived, but some persistent and challenging for our biochemistry to break down. These persistent AGEs lead to cross-links, binding together molecules in the extracellular matrix and thereby altering the structural properties of tissues. This is perhaps most harmful where it reduces tissue elasticity, and is thus an important contributing cause of skin and vascular aging. While sugars are involved, it is much debated as to whether the contents of diet, either fully formed AGEs from certain cooked and processed foods, or precursors in the form of excessive amounts of sugar, has

From https://www.fightaging.org/archives/2019/05/a-potential-approach-to-tackling-cel-and-cml-advanced-glycation-end-products/

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https://healthnews010.wordpress.com/2019/05/02/a-potential-approach-to-tackling-cel-and-cml-advanced-glycation-end-products/